Polymersomes as a potential platform for cancer immunotherapy

نویسندگان

چکیده

With the focus in field of cancer nanomedicine shifting from direct tumor targeting to modulation immune system, new opportunities arise for employment nanocarrier systems. Polymeric nanovesicles, or polymersomes, have been under investigation as a potential platform past decades. These investigations enhanced our fundamental knowledge on how tailor physicochemical properties, such size and shape, surface chemistry functionalization, membrane characteristics. The versatile nature high structural stability polymersomes makes them suitable treatment that goes beyond drug delivery. Rational design allows spatiotemporal control over function specific cell targets enhance immunotherapy. This review provides perspective view multifunctional vivo We discuss implement field, elaborate their considerations immunotherapeutic applications compare with lipid nanoparticles other relevant Current challenges future perspectives are addressed underline what is needed employ

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Study of NGEP expression in androgen sensitive prostate cancer cells: A potential target for immunotherapy

  Background: Prostate cancer is one of the leading causes of cancer deaths among men. New gene expressed in prostate (NGEP), is a prostate-specific gene expressed only in normal prostate and prostate cancer tissue. Because of its selective expression in prostate cancer cell surface, NGEP is a potential immunotherapeutic target. To target the NGEP in prostate cancer, it is essential to investig...

متن کامل

Potential of cancer-testis antigens as targets for cancer immunotherapy

Cancer-testis antigens are tumour antigens with limited expression in male germ cells in the testis, ovary and trophoblasts. Recently, their expression has been seen in different types of tumours. Due to the existence of the blood-testis barrier, testis is considered an immune-privileged site; and testis-specific genes, if expressed in cancers, can be immunogenic. For this reason, cancertestis ...

متن کامل

Immunotherapy for Breast Cancer Treatment

Breast cancer, as a heterogeneous disease, includes a wide range of pathological and clinical behaviors. Current treatment protocols, including radiotherapy, chemotherapy, and hormone replacement therapy, are mainly associated with poor response and high rate of recurrence. Therefore, more efforts are needed to develop alternative therapies for this type of cancer. Immunotherapy, as a novel str...

متن کامل

Virtual Space as a Platform for Student Research Practices

Online learning is becoming an increasingly popular request. Many universities are moving fully or partially to this form of study. In the article, the authors considered what is virtual space, what are its criteria, as well as applicability for teaching students and passing research practices. Based on an analysis of existing virtual spaces (platforms), an experiment was conducted. The study s...

متن کامل

Immunotherapy of Cancer

This article has no abstract.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Materials today advances

سال: 2022

ISSN: ['2590-0498']

DOI: https://doi.org/10.1016/j.mtadv.2021.100203